
relion prime manual
ReliOn Prime Manual: A Comprehensive Guide (Updated 12/16/2025)
Welcome! This guide provides detailed instructions for the ReliOn Prime Blood Glucose Monitoring System, ensuring accurate testing and effective diabetes management as of today, 12/16/2025.
The ReliOn Prime is a blood glucose monitoring system designed for individuals managing diabetes. It offers a convenient and accurate way to track blood sugar levels, empowering informed healthcare decisions. This system, updated as of December 16, 2025, builds upon previous ReliOn models – Classic, BLU, and Voice – incorporating user feedback and technological advancements.
Frequent glucose testing is crucial for effective diabetes control, and the ReliOn Prime facilitates this process. The system includes a meter, lancing device, test strips, and control solution, all working together to provide reliable results. Proper setup and understanding of the meter’s functions are essential for optimal performance.
This manual will guide you through each step, from initial setup and testing procedures to troubleshooting common error codes like Er1, Er2, Er3, and E04, often related to battery issues. Furthermore, we’ll cover syncing capabilities with Glooko for seamless data management and maintaining accurate time and date settings for successful synchronization.
What’s Included in the ReliOn Prime Kit
Upon opening your ReliOn Prime kit, you’ll find everything needed to begin monitoring your blood glucose levels effectively. The core component is the ReliOn Prime meter itself, designed for user-friendly operation and accurate readings. Alongside the meter, the kit contains a precision lancing device, used to obtain small blood samples with minimal discomfort.

A supply of ReliOn Prime test strips is included, essential for conducting the glucose tests. These strips are specifically designed for use with the ReliOn Prime meter, ensuring compatibility and reliable results. You’ll also receive a control solution, used to verify the meter and test strip functionality.
Additionally, the kit includes a user manual – this document – providing comprehensive instructions and troubleshooting guidance. A battery (typically a 2032 battery) is pre-installed, powering the meter. Finally, a quick reference guide offers a concise overview of key features and testing steps.
Setting Up Your ReliOn Prime Meter
Setting up your ReliOn Prime meter is a straightforward process, ensuring accurate readings from the start. First, insert the included battery, if not already installed, ensuring correct polarity. The meter will power on automatically and may prompt you to set the time and date – crucial for accurate syncing with Glooko, and for maintaining a detailed testing history.
To set the time and date, navigate through the meter’s menu using the buttons. Refer to the section on “Time and Date Settings” for detailed instructions. Ensure the date and time are correct to avoid syncing issues. The meter may also ask you to select your preferred units of measurement (mg/dL or mmol/L).
Before your first test, familiarize yourself with the meter display and its functions. A brief review of the “Understanding the Meter Display” section is recommended. Finally, confirm the battery is secure and the meter is functioning correctly.
Understanding the Meter Display
The ReliOn Prime meter features a clear, easy-to-read display providing essential information at a glance. The primary area shows your current blood glucose reading in your selected units (mg/dL or mmol/L). Below this, you’ll find indicators for meter status, including battery level and any active error codes – such as Er1, Er2, Er3, or E04 – which require attention.
A dedicated icon indicates when a test strip is properly inserted and ready for a blood sample. The display also shows the date and time, vital for accurate record-keeping and Glooko synchronization. Pay attention to any flashing symbols, as these often signal a specific condition or require user action.
Familiarizing yourself with these display elements will help you quickly interpret results and troubleshoot potential issues. Refer to the “Error Codes and Troubleshooting” section for detailed explanations of any error messages.
Blood Glucose Testing Procedure
Before testing, ensure your hands are clean and dry; Insert a new test strip into the ReliOn Prime meter; the meter will power on automatically. Prepare the lancing device with a fresh lancet, adjusting the depth setting to suit your skin type. Gently press the lancing device against the side of your fingertip to obtain a small blood sample.
Carefully apply the blood to the designated area on the test strip, ensuring sufficient sample volume. The meter will begin counting down, displaying the remaining time. Avoid smearing the blood or applying excessive pressure. Once the countdown reaches zero, your blood glucose reading will appear on the display.
Record your result and any relevant information, such as meal times or medication dosages. Proper technique is crucial for accurate readings.
Preparing the Lancing Device
The ReliOn Prime lancing device delivers a quick, controlled puncture to obtain a blood sample. First, remove the cap from the device. Insert a new, sterile lancet firmly into the lancing device, twisting to secure it. Never reuse lancets, as this can cause infection and inaccurate results.
Next, adjust the depth setting on the device. Start with a lower setting and increase it gradually until you obtain an adequate blood drop with minimal discomfort. Consider your skin type; thicker skin requires a deeper setting. Replace the cap securely.
Cock the lancing device by pulling back the plunger and releasing it. The device is now primed and ready for use. Always dispose of used lancets safely in a sharps container.
Applying Blood to the Test Strip
Ensure your hands are clean and dry before proceeding. Insert a new ReliOn Prime test strip into the meter, observing the correct orientation as indicated on the strip and meter. The meter will automatically turn on. Gently squeeze or massage your fingertip to encourage blood flow after using the lancing device.
Hold the edge of the test strip to the drop of blood. Do not smear the blood onto the strip; allow the strip to wick up the blood sample automatically. A sufficient sample volume is crucial for accurate results. Avoid applying too little or too much blood.
The meter will begin the testing process, displaying a countdown. Keep the strip in contact with the blood drop until the meter beeps or displays a result.
Reading and Interpreting Results

Once the ReliOn Prime meter displays your blood glucose reading, carefully note the number and the unit of measurement (mg/dL). Compare your result to your target range, as determined by your healthcare provider. Understanding your target range is vital for effective diabetes management.
Results outside your target range require attention. High readings may indicate the need for adjustments to your diet, exercise, or medication, while low readings may necessitate a quick source of glucose. Keep a log of your readings to identify patterns and share with your doctor.
Remember that results can be affected by various factors, including timing of meals, stress, and illness. Consistent testing and careful interpretation are key to maintaining optimal health.
Error Codes and Troubleshooting
The ReliOn Prime meter utilizes error codes to signal potential problems during operation. Recognizing these codes is crucial for effective troubleshooting. Common errors include Er1, Er2, Er3, and E04. Each code indicates a specific issue requiring attention.
Error Code Er1 often stems from issues with the test strip or insufficient sample volume. Er2 typically points to a problem with the test strip itself. Er3 may indicate an internal meter malfunction. E04 frequently relates to low battery levels, easily resolved with a battery replacement.

If an error code appears, consult the meter’s manual for detailed solutions. Attempting to repeat the test with a fresh strip and adequate blood sample is often the first step. If problems persist, contact ReliOn support for assistance.
Error Code Er1: Common Causes and Solutions

Error Code Er1 on your ReliOn Prime meter typically indicates a problem with the test strip or an insufficient blood sample. The most frequent cause is a damaged or improperly inserted test strip. Ensure the strip is correctly oriented and fully seated in the meter’s port.
Another common reason is applying an inadequate blood volume to the test strip. A small, smeared drop may not be sufficient for accurate reading. Gently apply a larger, raised drop, allowing it to fill the designated area completely.
If Er1 persists, try a new test strip from a different vial, as strips can degrade over time. Also, verify the expiration date on the vial. If the issue continues, a meter malfunction might be present, requiring contact with ReliOn support.
Error Code Er2: Identifying and Fixing the Issue
Error Code Er2 on the ReliOn Prime meter generally signals an issue with the meter’s internal components or a problem during the testing process. This error often arises from inconsistencies during the reading of the test strip, or a potential hardware fault within the device itself.
First, attempt a simple reset by removing and reinserting the test strip. If Er2 reappears, try a new test strip from a freshly opened vial to rule out strip defects. Ensure your hands are clean and dry before handling the strips to prevent contamination.
If the error persists despite these steps, it may indicate a more serious internal problem. In such cases, contacting ReliOn customer support is crucial for further diagnosis and potential meter replacement. Do not attempt to disassemble or repair the meter yourself.
Error Code Er3: Troubleshooting Steps
Error Code Er3 on your ReliOn Prime meter typically indicates a communication error between the meter and the test strip. This can stem from several factors, hindering accurate blood glucose readings. Initial troubleshooting involves carefully inspecting the test strip for any physical damage, like bends or cracks.

Ensure the test strip is inserted correctly into the meter’s port, following the directional arrow. A loose connection can trigger this error. Try a new test strip from a different vial, as the current batch might be faulty. Confirm the expiration date hasn’t passed.
If Er3 continues, power cycle the meter by removing the battery briefly, then reinserting it. If the issue remains unresolved, contact ReliOn support for assistance, as it could signify an internal meter malfunction.
Error Code E04: Battery Related Issues & Replacement
Error Code E04 on the ReliOn Prime meter signals low battery power. This is a common issue, easily addressed with a simple battery replacement. The meter utilizes a CR2032 3V battery, readily available at most pharmacies and retailers.
To replace the battery, gently open the battery compartment, typically located on the back of the meter. Remove the old battery, observing the correct polarity (+ and -) indicated inside the compartment. Insert the new CR2032 battery, ensuring proper alignment. Close the battery compartment securely.

ReliOn Prime battery replacement often resolves E04 errors and restores meter functionality. Always dispose of used batteries responsibly, following local regulations. A fresh battery ensures accurate readings and reliable performance.
Syncing with Glooko
Syncing your ReliOn Prime meter with the Glooko mobile app allows for convenient blood glucose data tracking and analysis. This feature enables you and your healthcare provider to monitor trends, identify patterns, and optimize your diabetes management plan.
Before syncing, ensure your meter is compatible with Glooko and that you have a stable internet connection on your smartphone or tablet. Download and install the Glooko app from your device’s app store. Follow the in-app instructions to create an account or log in.
Accurate time and date settings on your meter are crucial for successful syncing. Incorrect settings can cause synchronization failures. Refer to the “Time and Date Settings” section of this manual for guidance. Once configured, initiate the sync process through the Glooko app, following the on-screen prompts.
Time and Date Settings for Accurate Syncing
Maintaining the correct time and date on your ReliOn Prime meter is paramount for accurate data logging and seamless synchronization with the Glooko app. Discrepancies can lead to syncing issues, hindering effective diabetes management and reporting to your healthcare team.
To adjust the time and date, navigate to the “Settings” menu on your meter. Consult the meter’s display and button functions detailed in the “Understanding the Meter Display” section for specific instructions. Carefully input the current date (month, day, year) and time (hour, minute) using the meter’s controls.

Double-check your entries to ensure accuracy before saving. An incorrect time or date will prevent successful data transfer to Glooko. Regularly verify these settings, especially after battery replacements or if you travel across time zones. Accurate settings guarantee reliable data for informed decision-making.
Battery Replacement
Maintaining a fresh battery is crucial for the consistent operation of your ReliOn Prime meter. A low battery can cause inaccurate readings, error messages (like E04), and ultimately, prevent successful glucose monitoring. The meter utilizes a standard 2032 battery, readily available at most pharmacies and retailers.
To replace the battery, gently open the battery compartment, typically located on the back of the meter. Remove the old battery, observing the correct polarity (+ and -). Insert the new 2032 battery, ensuring proper alignment. Close the battery compartment securely.
After replacement, the meter may automatically reset. Verify the time and date settings (see “Time and Date Settings for Accurate Syncing”) as they may revert to default. A new battery often resolves error codes and restores optimal meter functionality. Dispose of used batteries responsibly, following local regulations.
Maintaining Your ReliOn Prime Meter
Regular maintenance ensures the longevity and accuracy of your ReliOn Prime meter. Keep the meter clean by wiping it with a slightly damp cloth after each use; avoid harsh chemicals or abrasive cleaners. Store the meter in a cool, dry place, away from extreme temperatures and direct sunlight.
Periodically inspect the test strip port for debris and gently clean if necessary. Ensure the lancing device is also kept clean and stored properly. Always check the expiration dates of test strips – expired strips can yield inaccurate results.
Proper battery care (see “Battery Replacement”) is essential. Avoid dropping the meter, as this can damage internal components. If issues arise, consult the troubleshooting section or contact ReliOn support for assistance. Consistent care will help maintain reliable performance.
ReliOn Prime vs. Other ReliOn Models (Classic, BLU, Voice)
The ReliOn Prime represents an advancement over previous ReliOn models like the Classic, BLU, and Voice meters. While all models perform basic blood glucose testing, the Prime often features improved accuracy and potentially faster results. The Classic and BLU are older models, potentially lacking the Prime’s enhanced features.
The Voice meter offers audible results, beneficial for visually impaired users, a feature not standard on the Prime. However, the Prime generally boasts a more modern design and potentially better data management capabilities. Error code displays differ across models; the Prime’s codes are detailed in the troubleshooting section.
Battery replacement is simpler on the Prime (using a 2032 battery), and syncing with Glooko is often more streamlined. Consider your individual needs when choosing a model – the Prime offers a balance of features and reliability.
Frequently Asked Questions (FAQ)
Q: What does error code Er1 mean? A: Er1 typically indicates a test strip issue – ensure proper insertion and check the expiration date. Q: Why is my meter showing Er2? A: Er2 often signals a problem with the meter’s internal components; contact ReliOn support.
Q: How do I fix an Er3 error? A: Er3 usually relates to insufficient blood sample; retest with a larger drop. Q: What causes error code E04? A: E04 indicates low battery; replace the 2032 battery immediately.
Q: Can I use any test strips with the ReliOn Prime? A: No, use only ReliOn Prime test strips for accurate results. Q: Why is syncing with Glooko failing? A: Verify the correct time and date settings on your meter. Incorrect settings can cause syncing issues.
Q: Where can I find more help? A: Contact ReliOn support directly for assistance with any unresolved issues.
Contacting ReliOn Support
Need assistance with your ReliOn Prime meter? ReliOn provides several avenues for customer support to address any concerns or issues you may encounter. For immediate help with error codes, troubleshooting, or general inquiries, reaching out to their dedicated support team is recommended.
While specific contact details aren’t explicitly provided in the available information, past user experiences suggest ReliOn is generally responsive to customer issues. You can typically find contact information – including phone numbers and email addresses – on the official ReliOn website or packaging.
Don’t hesitate to contact them if you’ve experienced problems with your meter, such as inaccurate readings, error messages, or difficulties syncing with Glooko. They are equipped to guide you through troubleshooting steps and offer solutions.
Dance Choreography: “House of Bamboo” (This City is Ours)
A delightful diversion! While focused on health, let’s explore a fun activity. “House of Bamboo” (also known as “This City is Ours”) is a line dance choreographed by Emma Weissensteiner and adapted by Maggie Stevenson (SCO) in April 2025.
This beginner-level dance, set to Andy Williams’ “House of Bamboo,” features 32 counts with 4 walls. Maggie Stevenson taught the dance based on Emma Weissensteiner’s original steps from a BBC TV show, receiving Maggie’s approval for the adaptation. It’s described as a “fun little dance” frequently requested by dance enthusiasts.

The choreography is suitable for all levels, offering a lighthearted break. Resources, including videos, are available online for learning the steps. Enjoy this charming dance!
Choreographer Information: Emma Weissensteiner & Maggie Stevenson
Creative minds behind the moves! Emma Weissensteiner originally choreographed the “House of Bamboo” line dance, drawing inspiration from a BBC television series. Her initial steps formed the foundation for this enjoyable dance routine, captivating audiences with its charm and simplicity.
Maggie Stevenson (SCO) skillfully adapted Emma’s choreography in April 2025, bringing a fresh perspective while honoring the original’s essence. Maggie’s version is widely taught and enjoyed in line dance classes, praised for its beginner-friendly nature and engaging rhythm.
Both choreographers demonstrate a passion for dance and a commitment to creating accessible routines. Their collaborative spirit has resulted in a dance that brings joy to participants of all skill levels, offering a delightful and active experience.